NeuroMeghnaSarathy
Meghna Sarathy
My Ethical Investigation Research
My research delved into crucial inquiries and ramifications pertinent to the exploration of Promoting Resilience for Depressed Adolescents and its prospective trajectory. We transitioned from what neuroscience enables to what it morally necessitates.
The incorporation of resilience training into school curricula presents various ethical, legal, and social implications, particularly concerning the treatment of adolescent depression. Ethically, it addresses concerns of over-prescription of antidepressants, often driven by pharmaceutical interests, by promoting non-pharmacological interventions. This can mitigate the risk of side effects and dependency associated with these medications, particularly in vulnerable populations such as the elderly. Legally, the implementation of cognitive behavioral therapy (CBT) principles in schools raises issues regarding the qualifications of educators and the need for appropriate training to ensure effectiveness and avoid potential harm. Socially, fostering resilience through positive social psychological interventions can reduce the stigma associated with mental health issues, encouraging a healthier dialogue and understanding among adolescents. However, challenges such as parental consent and the perception of “toxic positivity” must be navigated carefully to avoid reinforcing harmful attitudes. The approach also needs to balance resilience-building with acknowledging and addressing negative emotions appropriately. Overall, integrating resilience training within educational systems holds promise for reducing the prevalence of depression among adolescents, fostering long-term mental health benefits, and potentially decreasing reliance on pharmaceutical treatments.
My Ethical Analysis
Presentation
In the Advanced Medical Neuroscience Internship, I worked directly with some of the world’s leading scientists to learn about neuroethics, neurocognitive health, and revolutionary developments in the field.
I had the honor of presenting my research to a distinguished panel of judges, among them Dr. James Giordano, Chief of Georgetown University’s Neuroethics Studies Program.
My presentation aimed to engage in discourse and shed light on the ethical considerations inherent in reviewing research about Promoting Resilience for Depressed Adolescents for the esteemed judges.
The Frontier of Neuroscience
Center for Functional and Molecular Imaging
The Center for Functional and Molecular Imaging (CFMI) at Georgetown is one of the world’s leading institutions with expertise in structural, functional, and brain imaging.
While visiting the CFMI, I met Dr. Ashley VanMeter, Director of the Neuroimaging Corps at Georgetown University, who described to me the rationale, protocols, capabilities, and limitations of functional magnetic resonance imaging for clinical and basic science applications.
I not only learned about the science behind fMRI, but also had the opportunity to see a machine that possesses a magnetic power of 30,000 times the strength of Earth’s magnetic field.
Neuromodulation
Neuromodulation is a technology that electrically stimulates nerves or chemically targets neurological sites to treat a vast array of conditions and symptoms.
I specifically learned about transcranial direct current stimulation and the neuromodulation devices available for public purchase. These technologies provide external electrical stimulation through a helmet or headband of electrodes.
To further demonstrate the applications of neuromodulation, we learned about electrical stimulation, perception of stimuli, and used the electrical activity captured from flexing my own muscle to contract the muscle of another intern. Through this, we could control each other’s arms!
Internship Highlights
- Dr. James Giordano
- Deep Brain Stimulation
- The Creative Brain
- Experts & Mentors
I had the chance to work and collaborate directly with Dr. James Giordano, Chief of Georgetown University’s Neuroethics Studies Program.
In addition to his involvement with a variety of educational institutions, Dr. Giordano is the author of over 350 publications in neuroscience and neuroethics.
During our first meeting, Dr. Giordano guided us through an exploration of our own brains, minds, and selves, probing for the problems, meanings, and questions within the world that surrounds us.
In subsequent meetings, Dr. Giordano frequently prompted both introspection and extrospection to encourage familiarity with our own minds, as well as our environment, and how the two can interact to our benefit.
I had the unique opportunity to learn from Dr. Michael Okun, a neurologist, neuroscientist, and founder of the University of Florida’s Movement Disorders Program.
The university’s program aims to provide interdisciplinary and integrated care that facilitates communication between all members of their team to provide the best care possible.
Within his work, Dr. Okun utilizes Deep Brain Stimulation (DBS), which operates like a pacemaker within the brain and is often inserted via conscious surgery.
During this operation, electrodes are put in the brain to regulate electrical signals and help with conditions like Epilepsy, Parkinson’s Disease, Dystonia, Obsessive Compulsive Disorder, and Essential Tremor.
I had the opportunity to discuss stimulating creativity through brain science with Dr. Adam Green, the Director of the Lab for Relational Cognition at Georgetown University.
Dr. Green maintains that creative insights are “the product of connections made between things other people didn’t put together,” and we explored the neurological foundations of this theory.
In one of his most prominent experiments, Dr. Green had participants draw the analogies to evaluate semantic distance and creativity as explained above, but also regarded the potential role of neuromodulation.
tDCS is transcranial direct current stimulation, which is a non-invasive “helmet” of sorts that allows for the modification of the neural pathways’ firing in the brain. The external stimulator is placed on the scalp and then provides electrical stimulation to a broad region in order to control the neurons’ firing. We also had a chance to observe and try neurofeedback technology that uses how we learn to help us train our brains in real time!
Along with Dr. Giordano, I had the opportunity to work closely with Dr. Rachel Wurzman, a Dana Foundation Fellow in Neuroscience and Society.
Dr. Wurzman encouraged us to think critically about the questions that help drive science forwards and improve our understanding of the world around us through a biopsychosocial lens. She also lent her expertise of neuroplasticity, neurodiversity, and neuroethics to help our team develop our research proposal.
In addition to our work with Dr. Wurzman, we had the opportunity to meet with a variety of neuroscientists with a variety of unique specialities.
One such professional was Dr. Fernando Pagan, a Georgetown Neurologist and the Director of Movement Disorders, who is a nationally recognized leader in Parkinson’s Disease treatment. We were able to learn about Movement Disorders from various perspectives as Dr. Pagan was joined by Captain Rick Schena, who lives with Parkinson’s and explains how his treatment plan allows him to still do what he would like to do.